The Bioinformatics and High Performance Computing (HPC-BIO) Group of the UCAM investigate, along with structural bioinformatics expert, Dr. Hugo Verli, the characteristics of flexibility of proteins that interact in the development of diseases such as thrombosis.
"These diseases are often related to a change in the form of proteins or, in other words, its flexibility. Knowing these properties will help to design new active ingredients of drugs, much more effective," says the guest researcher.
For three months, Dr. Verli, professor at the Universidade Federal do Rio Grande do Sul (Brazil), will work in the UCAM with Dr. Horacio Emilio Pérez Sánchez to investigate the conformational dynamics of proteins such as antithrombin, one of the main involved in the control of blood clotting.
The stay of this research, funded by the call Jimenez Sword of the Seneca Foundation, aims to determine aspects such as the flexibility of the structure of the building blocks of proteins and pharmaceutical compounds, which is a major step in the development of new drugs that will multiply its potential to treat these diseases.
Source: UCAM