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The prestigious Journal of the American Chemical Society (JACS) of the American Chemical Association, one of the best in the world, publishes the findings in the research of Professor Dr. José Pedro Cerón, a member of the BIO-HPC Group of the UCAM, to improve the efficacy of a drug against a wide range of cancers and reduce the side effects of current treatments

After having starred in several covers in the journals of the Royal English Society of Chemistry and the Royal Spanish Society of Chemistry, the latest work of the expert in drug simulation now stars on the cover of the prestigious journal JACS, published by the American Chemical Association .

On this occasion the professor of the UCAM, Dr. José Pedro Cerón Carrasco, has the collaboration of the team of Professor Andrea Melchior of the University of Udine (Italy), to discover the mechanism of the attack of the drug on the tumor.

The work of these researchers has revealed data as encouraging as the true mechanism of action on the tumor of the drug discovered by one of the best research groups in this area of ​​the Massachusetts Institute of Technology (MIT), to reduce the side effects of chemotherapy .

Researchers have worked with the new molecule called fenantriplatin, recently designed by the MIT group in the United States, on which until now the complete mechanism by which the attack on the tumor DNA, which is its final target, was not known.

Clinical trials indicate that fenantriplatin may be more effective than the treatments used so far in chemotherapy.

In fact, the main advantage of this new drug is its effectiveness against a wide range of cancers and their qualities to reduce the side effects of current therapies.

"Our work allows us to better understand how the reaction of fenantriplatin with DNA occurs, which is key to explaining the origin of the beneficial activity of this new drug." The results we publish can be used not only to interpret the data obtained at MIT , but also can be used to propose other drugs that are even more effective against cancer cells ", states Dr. Cerón.

Source: UCAM